These statements have not been evaluated by the Food and Drug Administration. And already you posted the abstract above. Here it is copied below: Re strontium citrate not specifically being shown in the research: It has been clearly stated in the research that the strontium ions, NOT ranelic acid (ranelate) are what are producing the beneficial effects on bone. You could try taking 150 mg of magnesium citrate along with your Strontium Boost. Hi Peter, and not the strontium citrate. I typically give my 75lb boxer a can of sardines once a week and I give it to him all at once. We now have evidence that the degree of mineralization of bone tissue strongly influences not only the mechanical resistance of bones but also the bone mineral density. My third suggestion for you is to have your doctor order a 24 Hour Urine test to check all your hormone levels best lab for this is Meridian Valley Labs. I am presently taking New Chapter Bone Strength Take Care. Which of the LE products do you recommend? Im on an estrogen-blocker after having had breast cancer three years ago. A couple of months ago I saw new research suggesting that some people (a VERY few of us, obviously including the woman who wrote me) may be able to get by with less K2 these are persons with some rare SNPs that result in their keeping K2 around longer than the vast majority of us. Hi Kay, I, therefore, thank you for all this valuable information. Consumers of conventionally-grown foods are at risk of strontium deficiency, which, as you will soon see, is a factor that increases our risk of osteopenia/osteoporosis as we age. Personally, I expect to no longer be even borderline osteopenic by my next DXA (about 9 months from now) and as soon as that happens, I am going to run an n=1 trial, cut my strontium dosage in half and see how that works for me. http://www.lmreview.com/articles/view/select-the-right-hormone-test-for-your-patient-using-bio-identical-hormone-/ But let me reiterate, I am NOT paid to be a sales person for AlgaeCal. Regarding taking 1/2 the recommended dosage I have not seen anything in the research to indicate this would be better. Short-term toxicity of strontium chloride in rats. Heres what he reports from the following 2 papers he discusses that is relevant to your question: I have added the ones that were removed that apply to your question in my comments below: Strontium is almost twice as large as calcium, and its larger size does affect DXA readings. Natural strontium salts (strontium citrate) are safe when consumed in the correct dose and with the proper amount of calcium. It works best for me to take AlgaeCal Plus in the morning and evening and Strontium Boost with lunch. In female rats treated with strontium ranelate over 2 years, dose-dependent increases of bone strength and bone mass of the vertebral body (containing a large proportion of trabecular bone) and of the midshaft femur (containing mainly cortical bone) were detected without change in bone stiffness. The link you sent me goes to a website basing their claims on research conducted no later than 1993, so I checked PubMed to see if more recent papers had been published (which one would assume they would be if this therapy was helpful). LIPUS stimulation on metastatic bone tumors induces differentiation of osteoblasts without proliferation of tumor cells. I was diagnosed with osteoporosis last month & I started taking AgaeCal & Strontium Boost this month. I have corresponded with a number of leading researchers. Take a strontium break, but please also think about what has changed in the last couple of months that could be causing hair loss. PAHs are known to be capable of provoking autoimmune reactions, including DRESS, TENS and more. An acidic pH, which many of us typically have because we eat the standard Western diet, contributes to bone loss. Re the inflammation (which as you know promotes activation of osteoclasts, so we really need to get that down! I only have (1) one kidney so should I take the 2 supplements? A member of the American Medical Writers Association for more than 25 years, Lara publishes and reviews articles covering breaking research on bone health in Integrative Medicine: A Clinicians Journal. If any of these critters are present in your digestive tract, which is extremely common, they will co-opt the citrate and use it to fuel their own activities. I am turning 68 on July 1st and just started taking AlgaeCalPlus with the StrontiumBoost about a week ago. Bovine lactoferrin improves bone mass and microstructure in ovariectomized rats via OPG/RANKL/RANK pathway. I have been scared to take Strontium but am now wondering if should, I would be so grateful for your advice and suggestions, Just finished your book-absolutely brilliant. Meat from free range, pastured animals should be good for you when consumed in small amounts along with plenty of vegetables. shown in the research to be helpful. (The creatinine clearance rate is also called the glomerular filtration rate because tiny capillaries in the basic structural and functional unit of the kidney, the nephron, are called glomerular capillaries.). Vit D3 increases your bodys production of vit K dependent proteins, so you will make more of them and will need more K2 to activate them. Bottom Line for best absorption, take strontium separately from other minerals. AlgaeCal is clinically supported to improve bone density. Ask your doctor to get tested to know your current levels and how much you need to bring your levels up to the healthy range. Here are links to this research (I see only one of the papers I cited is now provided as a link in the post on AlgaeCal.com. Within 10 months of using AlgaeCal Plus, my 2012 DXA showed BMD 3.2% in my hip, and 6% in my spine from 2011. When I started him on this protocol about a year ago now, he was limping, wearing a knee brace, and fearing his bball playing days were over. I realize keeping the food diary is a bit of a nuisance, but this is the only way to see what YOU actually need, so it truly is well worth the effort and you only have to do it once unless your eating habits change dramatically. In brief, check this persons credentials (where did this man get his medical training? But, after reading all the current research (more than 70 papers) on strontium, I started taking it again at a half dose to ensure my bones remain healthy. PubMed, Web of Science, Scopus, HighWire and Google scholar) for all the articles by Meunier and found over 150 articles relating to strontium in which he was involved. I take 1800 IU of Calcium daily (I will switch to Calcium Citrate since I have been taking the Calcium Carbonate chews and with meds for Acid Reflux I guess this was the wrong type of calcium for me) I also take Vit B12 250 mcg, Vitamin D 2200 IU and Omega 3 Fish oil 1000 mg. Epub 2004 Sep 13. [emailprotected]. 2012 Oct;33(10):1277-84. doi: 10.1038/aps.2012.83. Monitoring bone strontium levels of an osteoporotic subject due to self-administration of strontium citrate with a novel diagnostic tool, in vivo XRF: a case study. In other words, whether your bone density increases or not, strontium reduces your risk of breaking a bone! It really helped put my mind at ease. The other two Plans also used AlgaeCals plant calcium, but in differing amounts (750 mg in Plan 2, 756 mg in Plan 3), and with differing amounts of vitamin D3 ( 1,000 IU in Plan 2; 1,600 IU in Plan 3) and other bone health ingredients. Youll know what will work best for you just find a time of day when you can take your strontium several hours (3 4 hours would be ideal) apart from consuming calcium. Likewise, the most common over-the-counter supplements are chemically bound to different molecules, such as citrate, lactate, carbonate, and gluconate. You should be taking both AlgaeCal Plus and their strontium product, which is called Strontium Boost (and which is strontium citrate). I suggest you consider taking both AlgaeCal Plus and Triple Power. Many factors in our current environment prevent us from getting sufficient iodine for optimal thyroid function. The scientific facts are so different from these assertions, its unclear why they publish such misinformation. Moderate correlation (with r(2) > 0.56) was also found for the expression levels of transporters in the duodenum of human and rat, which provides the molecular mechanisms for the similarity and correlation of drug absorption between two species. In addition to its antiresorptive activity, strontium was found to have anabolic activity in bone and thus may have significant beneficial effects on bone balance in normal and osteopenic animals. I switched to Algae-Cal after you recommended it. Read labels! You can definitely take your strontium first thing in the morning! AlgaeCal is untreated as it is clean and pure / Aquamin is bleached with Hydrogen Peroxide Strontium ranelate (PROTELOS), a new chemical entity containing stable strontium (Sr), was tested for its capacity to influence bone quality and quantity. Yet, iron supplements can cause stomach cramps, nausea, and diarrhea in some people. You simply must experiment and see what works best for you. My question is this (and I apologize if its been asked before): Stay well, Lara. Please consider investing in your health if you possibly can. Glad you found Laras information helpful, Sherry! Ranelic acids only claim to fame is that it is SUPPOSED to be inert. Spector. Doctors began studying gastric emptying times in the . By staggering your intake, you allow both supplements to be absorbed properly and effectively. You can further optimize your absorption of strontium by: Ensuring your intake of vitamin D3 is adequate. PMID: 27684387. DRIs for vitamin D are: J Biomed Mater Res A. It feels more comfortable for digestive purposes to take the Strontium, with other food rather than, for example, late at night before lying down in bed. What is the excretion of strontium citrate? Oh myso sorry I didnt read the fine print.it was right there! But, in people whose digestive tracts are infected with unfriendly bacteria, such as Clostridia, citrate can be co-opted by these bactera and used to fuel their metabolism. Hi Robert, And remember, your intake of calcium should be balanced by an intake of about half as much magnesium, so 600-750 mg of magnesium daily. But there are still several misconceptions about strontium citrate pills: Lets take a closer, research-based look at each of them. Thank you so much for all the information and support you have given us! [again, areas richer in trabecular bone] Lara, Keep working ,impressive job! Another quote from this paper on spine BMD improvements being most likely to be over-estimated . One other suggestion we order our fish from Vital Choices (www.vitalchoices.com) You can look at their website, see their products and their excellent quality control. Re your question above, best outcome would be if very little of either the strontium or the citrate were excreted. Re: Life Extension K2 There are two available K2 products from them. 10 bone essential supplements Review: 1. No worries! In fact, each has harmful side effects. How old are you? But I would strongly advise you NOT to use any dosage of this abnormal form of strontium! A personal note: this is my situation. Your thoughts on this would be most appreciated. I also discuss bone building exercises and diet. Any supplement providing 680 mg of elemental strontium in the form of strontium citrate will be fine. How quickly our kidneys filter creatinine from the bloodstream, which is called the creatinine clearance rate, provides a measure of how effectively your kidneys are filtering your blood. Kombucha is another excellent dairy-free source of pro-biotics. The strontium and increase in thyroid weight, that I had reference to, can be found in the thesis paper (cited above) in one of the literature review portions. You can take Triple Power Omega 3 Fish Oil right off the spoon (it's that tasty.) If you do decide to reintroduce it, we would suggest trying a half dose (1 capsule) to start. In addition I take 5 mg of Vitamin K4 (menatetrenone). 2. this does not seem like it honors the natural biological process of building bone structure. So, they were looking at short term (in comparison to the rest of a postmenopausal womans life span) outcomes. Strontium distribution and interactions with bone mineral in monkey iliac bone after strontium salt (S12911) administration. Strontium (Citrate) is an alkali earth metal, very similar in structure to Calcium, and has a similar effect in the body. PHD, MBA - Head of Research & Development Center of Bone Diseases, Lausanne University Hospital CHUV, Switzerland. The PubMed research indicates just the opposite is true. currently doing his residency in Emergency Medicine; my daughter, who is 40 years old and an MS, RD nutritionist, and my husband, Dr. Joe Pizzorno, taking AlgaeCal Plus along with me we all take the full dose daily. It generally takes 4 to 5 hours for the stomach to empty after a full meal and a bit less after a snack or liquid, though it varies depending on how much and what kind of food you ate. At all the applied doses, incorporation of strontium produced no significant change in the crystal lattice parameters, even if the ionic radius of Sr21 (1.13 ) is slightly larger than that of Ca21 (0.99 ) (Table 1). YOUR best solution is highly likely to be around 180 mcg of K2 as MK-7. One very important factor to consider is vitamin A. Vitamin A is the key nutrient required for immune tolerance (vitamin A is involved in causing the immune system to produce regulatory T cells of the IL-10 strain, which help tune down and resolve inflammation), and many of us are not getting adequate vitamin A, which also works in partnership with vitamin D and should be consumed in comparable amounts for the optimal benefits derived from both nutrients. Strontium ranelate improves bone resistance by increasing bone mass and improving architecture in intact female rats. Strontium is eliminated by our kidneys, so it may accumulate in patients with chronic kidney disease whose kidneys ability to filter the blood of EVERYTHING, not just strontium, is compromised. But remember, YOUR body may prefer a lesser dose, period. 2012 Mar 26;12(1):12. I need to make sure there is not any contradictions between the heart meds and supplements for bones. 5.0 out of 5 stars Bone Health. PMID: 26699669, [No authors listed] Strontium still authorised despite an unfavourable opinion of the European Pharmacovigilance committee. I sure wish I could just take 1 pill, but reality is that this would not do the job for me. I have a green smoothie at least 5 days a week with collards or kale. Springdale clinic where we can get suggestions on mental health issues. Natural strontium salts, (strontium citrate), are safe (. Absorbed ranelic acid is rapidly eliminated unchanged via the kidneys., http://www.ema.europa.eu/docs/en_GB/document_library/Referrals_document/Protelos_and_Osseor/European_Commission_final_decision/WC500173031.pdf, Neither statement appears to be consistent with current research. I am not familiar with the Garden of Life product what are they saying may be harmful to a growing fetus? Meunier, P. J., Roux, C., Seeman, E., Ortolani, S., Badurski, J. E., Spector, T. D., The most recent study showed higher levels of DHEA were associated with 0.49% less bone loss at the neck of the femur (Ghebre MA, Hart DJ, Hakim AJ, et al. Be well, Lara. http://ukpmc.ac.uk/theses/ETH/2476. I was thinking of ordering mine from Vita Cost but see brands. postmenopausal vertebral osteoporosisa 2-year randomized placebo controlled I bought some and was determined to eat it regularly. Rely on Science, not rumor. Since your supplement is giving you 750 mg of strontium in 3 capsules, it looks like you are taking a different strontium citrate supplement. You eat lots of fiber. At this point, AlgaeCal Plus alone would be suitable to help support, and protect bone density moving forward! How is your digestion otherwise? I hope this information is helpful to you and encourages you to give AlgaeCal a try. 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